NoteParadoxical Effect of Synthetic Action of Aminoglycosides Hydroxy JSsu Isothiocyanates on Antimicrobial
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چکیده
antimicrobial synergism with streptomycin (SM) against Escherichia coli. On the course of those experiments, a peculiar suppression of SM by a low concentration of hlTC was observed, besides the antibacterial synergism of hlTC with SM. Further, bactericidal actiyity of SM in physiological saline was reduced by addition of hlTC. Time course experiments proyed that the antagonistic effect of hlTC occurred in an early stage after exposure of bacterial cells to SM. .
منابع مشابه
Paradoxical effect of synthetic hydroxy isothiocyanates on antimicrobial action of aminoglycosides.
Hydroxy isothiocyanates, especially 2-(4-hydroxyphenyl)ethyl isothiocyanate (hITC), were examined for antimicrobial synergism with streptomycin (SM) against Escherichia coli. On the course of those experiments, a peculiar suppression of SM by a low concentration of hITC was observed, besides the antibacterial synergism of hITC with SM. Further, bactericidal activity of SM in physiological salin...
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